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目的对细菌性肺炎患儿病菌分布状况进行探究,同时检测多效生长因子、C-反应蛋白两者与细菌性肺炎患者的联系以及诊断价值。方法本文研究数据来源为本院2013-2016年期间收治确诊细菌性肺炎患儿100例相关基线资料,根据感染程度将其以每组50例分为A组(轻度感染)和B组(重度感染),另选本院同期常规体检提示为健康儿童50例为对照组。对各组儿童各种临床资料进行回顾性分析,归纳A组、B组患儿病原菌分布以及3组对象临床指标如C-反应蛋白、多效生长因子、肿瘤坏死因子α、白细胞介素。结果对细菌性肺炎患儿分离细菌鉴定后提示主要为革兰阴性菌;相对于对照组指标,A组、B组各项指标数据提示均明显提高,B组患儿指标提高程度更为明显,组间数据统计学处理(P<0.05),均有显著差异。结论对细菌性肺炎患儿需做好病原菌感染防护措施,出现感染情况后患儿血清炎症因子指标显著提升,可作为对病情了解的一个重要指标,对指导制定治疗方案有重要意义。
Objective To investigate the distribution of bacteria in children with bacterial pneumonia and to explore the relationship between the multi-effect growth factor and C-reactive protein in patients with bacterial pneumonia and its diagnostic value. Methods The data of this study were from 100 patients with confirmed bacterial pneumonia in our hospital from 2013 to 2016. According to the degree of infection, they were divided into group A (mild infection) and group B (severe Infection), another hospital routine examination prompted the same period for the healthy children 50 cases for the control group. The clinical data of each group were retrospectively analyzed, and the distribution of pathogens in group A and group B were summarized. The clinical indexes such as C-reactive protein, pleiotropic growth factor, tumor necrosis factor alpha and interleukin in three groups were summarized. Results Bacterial isolates from children with bacterial pneumonia were mainly Gram-negative bacteria after bacterial identification. Compared with control group, the data of A, B group were all significantly improved, and the improvement of B group was more obvious. Data between groups were statistically significant (P <0.05), there were significant differences. Conclusion Bacterial pneumonia in children need to take protective measures of pathogenic bacteria infection, the occurrence of infection in children with serum inflammatory factor index increased significantly, as an important indicator of the disease to understand and guide the development of treatment programs are of great significance.