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目的调查评估麻城市2011年健康人群中百日咳、白喉和破伤风抗体水平。方法随机抽取健康人群血清480人份,分为六个年龄组,采用ELISA法检测百日咳IgG、白喉IgG和破伤风IgG。结果百日咳IgG、白喉IgG和破伤风IgG保护率分别为21.04%、73.33%和67.71%。3~6岁与7~14岁白喉抗体保护率分别为90%和76.67%,两年龄段抗体保护率差异有统计学意义(χ2=29.73,P<0.01);3~6岁与7~14岁破伤风抗体保护率分别为93.33%和66.67%,两年龄段抗体保护率差异有统计学意义(χ2=40.52,P<0.01)。结论麻城市人群中百日咳抗体水平较低,6岁以后人群中白破抗体水平下降明显。
Objective To investigate and evaluate the levels of pertussis, diphtheria and tetanus antibodies in healthy population in Macheng City in 2011. Methods 480 healthy volunteers were randomly divided into six age groups. Pertussis IgG, diphtheria IgG and tetanus IgG were detected by ELISA. Results The protective rates of pertussis IgG, diphtheria IgG and tetanus IgG were 21.04%, 73.33% and 67.71% respectively. The protective rates of diphtheria of 3-6 years old and 7-14 years old were 90% and 76.67%, respectively, and there was significant difference between the two age groups (χ2 = 29.73, P <0.01). The protective rates of 3-6 years old and 7-14 The protective rates of the annual tetanus antibodies were 93.33% and 66.67%, respectively. There was a significant difference in antibody protection rate between the two age groups (χ2 = 40.52, P <0.01). Conclusion The level of pertussis antibody in Majiang City is low, and the level of white-level antibody in people after 6 years old is obviously decreased.