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作者应用HAP—DAP方案治疗急性非淋巴细胞白血病(急非淋)34例,完全缓解(CR)率达79.4%,部分缓解(PR)率5.9%。获得高缓解率的关键是化疗药物的交替与大剂量应用,早期使骨髓增生程度降至低下,容易达到CR,测定骨髓原始细胞减少指数不仅可以指导化疗,也有预报疗效的价值。
In the 34 cases of acute non-lymphocytic leukemia (HFS) treated with HAP-DAP regimen, the complete remission (CR) rate was 79.4% and the partial remission (PR) rate was 5.9%. The key to obtain a high response rate is the alternation and high dose of chemotherapy drugs. The degree of myeloproliferation can be lowered to a low level in the early stage and the CR can be easily achieved. Determining the index of myeloblastosis can not only guide chemotherapy but also predict the therapeutic value.