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分散在水介质中的磷脂双层泡囊(脂质体),现已在化妆品和润肤剂及诊断剂中作载体之用,市场上也有以脂质体为基质的人用非肠道及皮肤用药。不久的将来,人们期望它可作为溶解亲脂性药物、活性及惰性靶向药物、缓释药物(如蛋白质类)及抗原等制成的脂质体制剂。1980年以前对研究药用脂质体不够重视,近10年来才受到学术界和药厂的重视,不论脂质体在体外(制备、特性和稳定性)和体内有(处理过程)对其特性都有新的和更好的领会。但有关脂质体的大规模制备、
Phospholipid bilayer vesicles (liposomes) dispersed in an aqueous medium are now used as carriers in cosmetics and emollients and diagnostics, and liposome-based human parenteral and Skin medication. In the near future, it is expected that it can be used as a liposome preparation made of lipophilic drugs, active and inert targeting drugs, sustained release drugs (such as proteins) and antigens. Prior to 1980, the study of medicinal liposomes did not pay enough attention, and in the past 10 years, it has received the attention of academia and pharmaceutical companies. Whether liposomes are in vitro (preparation, property and stability) and in vivo (process) There are new and better comprehensions. However, the large-scale preparation of liposomes,