论文部分内容阅读
目的临床观察原发于头面部恶性淋巴瘤的临床特征、诊断治疗过程及预后情况。方法对1994年1月~2001年12月收治的256例恶性淋巴瘤中的24例原发于头面部恶性淋巴瘤的临床资料及随访情况做临床分析。结果24例原发于头面部恶性淋巴瘤涉及鼻腔、韦氏环、涎腺各个部位,临床表现各异,难以明确诊断,平均误诊或漏诊4.9个月,曾被误诊为慢性鼻炎、上颌窦炎、慢性扁桃体炎,有3例被诊断为鼻咽癌及恶性肉芽肿。24例均经病理、免疫组化诊断。治疗采用放疗、放疗加化疗等,其中随访3年以上19例,3年生存率达63.2%。结论原发于头面部的恶性淋巴瘤临床表现不典型,易误诊漏诊,应尽早活检明确诊断,避免直接手术治疗,选择适当治疗方案,以提高疗效。
Objective To observe the clinical features of primary malignant lymphoma in the head and face and to diagnose the course of treatment and prognosis. Methods From January 1994 to December 2001 in 256 cases of malignant lymphoma in 24 cases of primary facial malignant lymphoma clinical data and follow-up clinical analysis. Results 24 cases of primary facial malignant lymphoma involving the nasal cavity, Wechsler ring, salivary glands in various parts of the clinical manifestations, difficult to confirm the diagnosis, the average misdiagnosis or missed diagnosis 4.9 months, had been misdiagnosed as chronic rhinitis, maxillary sinusitis , Chronic tonsillitis, 3 cases were diagnosed with nasopharyngeal carcinoma and malignant granuloma. All 24 cases were diagnosed by pathology and immunohistochemistry. Treatment with radiotherapy, radiotherapy and chemotherapy, of which 19 cases were followed up for 3 years, 3-year survival rate of 63.2%. Conclusions The clinical manifestations of primary malignant lymphoma in head and face are not typical and are easily misdiagnosed and missed. Biopsy should be diagnosed as early as possible to avoid direct surgical treatment and to select appropriate treatment regimen to improve curative effect.