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人类在劳动活动中与有害因素接触引起健康的伤害,需要进行大量的动物实验,包括毒理学、药理学、血液学、生化、免疫学和组织病理学等的实验,以模拟人的机体反应,依此提出有效的防治措施,保障人民身体健康和生产任务的完成。由于动物实验在实验设计,反应模拟和评价上问题多、误差大,有必要提出有关这方面的讨论意见,以供参考。一、动物实验的设计职业性有害因素的动物实验是将一种工业毒物或粉尘,通过不同的途径进入机体和引起的毒性作用—中毒。中毒是否由外源性或内源性、化学性或物理化
Human health hazards caused by contact with harmful factors in labor activities require a large number of animal experiments, including toxicology, pharmacology, hematology, biochemistry, immunology and histopathology to simulate the human body’s response, Therefore, effective prevention and control measures are put forward to ensure the people’s health and the completion of production tasks. As animal experiments in the experimental design, reaction simulation and evaluation of the problem, the error is large, it is necessary to put forward the discussion in this regard for reference. First, the design of animal experiments Occupational harmful factors in animal experiments is an industrial poison or dust, through different channels into the body and caused by toxic effects - poisoning. Whether the poisoning is exogenous or endogenous, chemical or physical