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研究初步表明,卵巢癌家族史妇女上应性卵巢癌的发病率较正常人群至少高3倍,有鉴于此,作者等于1990年7月至1992年12月所在家族性卵巢癌研究中心(FOCC)对386名该类妇女进行卵巢癌筛查,方法有经阴道超声成像(TVS),彩色多普勒血流显像及CA-125放免测定。研究对象年龄≥25岁,平均41岁。家族中至少有1个一级亲属和/或2个二级亲属为已确诊的卵巢癌患者。绝经前及绝经期各有328例(85.0％)和58例(15.0％)。研究对象于月经期、卵泡期和黄体期抽血测定,重复2～3周期,并严格依内分泌时相变化。所采标本置O℃待检。CA125以放免法(RIA)测定,≥35U/ml为异常。月经期或卵泡早期行TVS,若一侧
Preliminary studies have shown that the incidence of ovarian cancer in women with a family history of ovarian cancer at least 3 times higher than the normal population, in view of this, the author is equal to July 1990 to December 1992 where the FOCC (FOCC) A total of 386 women with ovarian cancer were screened by transvaginal sonography (TVS), color Doppler flow imaging and CA-125 radioimmunoassay. Subjects aged ≥25 years, mean 41 years old. At least one first-degree relative and / or two second-degree relatives in the family are already diagnosed ovarian cancer patients. There were 328 (85.0%) and 58 (15.0%) patients pre-menopausal and menopausal. Subjects in the menstrual period, follicular phase and luteal phase blood determination, repeated 2 to 3 cycles, and strictly according to the endocrine phase changes. The specimens were taken O ℃ to be seized. CA125 by radioimmunoassay (RIA), ≥ 35U / ml is abnormal. Menstrual period or early follicular line TVS, if one side