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目的探讨国产泮托拉唑治疗上消化道出血的疗效。方法全部病例分为小剂量组38例,大剂量组34例进行研究。小剂量组给泮托拉唑40mg.Bid每天静滴;大剂量组给泮托拉唑80mg.Bid每天静滴。结果小剂量组中显效26例,有效10例,有效止血率94.7%,大剂量组中显效25例,有效8例,有效止血率97%,两组经统计学比较,χ2值为0.0096,P>0.05,无统计学意义,两组差异无显著性。两组总有效止血率为95.8%,效果优良。结论国产泮托拉唑治疗上消化道出血疗效肯定,安全,并且不需要盲目加大剂量,40mg.Bid静滴是较理想的选择。
Objective To investigate the efficacy of domestic pantoprazole in the treatment of upper gastrointestinal bleeding. Methods All cases were divided into small dose group 38 cases, high dose group 34 cases were studied. Small dose group to pantoprazole 40mg.Bid intravenous infusion; high-dose group to pantoprazole 80mg.Bid daily intravenous infusion. Results In the low-dose group, 26 cases were markedly effective, 10 cases were effective, the effective hemostasis rate was 94.7%, 25 cases were effective in high-dose group, 8 cases were effective, and the effective hemostasis rate was 97%. The χ2 value was 0.0096 > 0.05, no statistical significance, no significant difference between the two groups. The total effective hemostasis rate of two groups was 95.8%, the effect is good. Conclusion Domestic pantoprazole treatment of upper gastrointestinal bleeding sure, safe, and do not need to blindly increase the dose, 40mg.Bid intravenous infusion is the ideal choice.