论文部分内容阅读
目的探讨纳洛酮对呼吸衰竭老年患者甲状腺激素的影响。方法选取2013年5月至2015年5月广东省江门第二人民医院收治的88例呼吸衰竭患者作为研究对象,按随机数字表法将其分为对照组和研究组,每组44例。对照组患者予以常规治疗,同时给予尼可刹米,研究组患者在常规治疗基础上采用纳洛酮进行治疗,比较两组患者三碘甲状腺原氨酸(T3)、甲状腺素(T4)、血清促甲状腺素(TSH)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)水平。结果治疗后,研究组患者的T3、T4、FT3、FT4水平均明显高于对照组,差异均有统计学意义(均P<0.05),但两组患者的TSH水平差异无统计学意义(P>0.05)。结论纳洛酮可有效提高呼吸衰竭老年患者甲状腺激素水平,改善其呼吸状况。
Objective To investigate the effect of naloxone on thyroid hormones in elderly patients with respiratory failure. Methods From May 2013 to May 2015, 88 cases of respiratory failure patients admitted to Jiangmen Second People’s Hospital of Guangdong Province were selected as research objects. According to the random number table, they were divided into control group and study group, 44 cases in each group. Patients in the control group were treated routinely with nikethamide. Patients in the study group were treated with naloxone on the basis of routine treatment. The levels of triiodothyronine (T3), thyroxine (T4), serum Thyrotropin (TSH), free triiodothyronine (FT3), free thyroxine (FT4) levels. Results After treatment, the levels of T3, T4, FT3 and FT4 in the study group were significantly higher than those in the control group (all P <0.05), but there was no significant difference between the two groups (P > 0.05). Conclusion Naloxone can effectively improve thyroid hormone level and improve respiratory status in elderly patients with respiratory failure.