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本研究应用口腔癌前病变动物模型，从活体照相、组织学和微血管等方面，对低频脉冲电刺激作用于口腔癌前病变进行观察，空白对照组肉眼可见肿瘤组织大量生成，１００％病变发生癌变。低频脉冲电刺激组肿瘤生成少见，３３．３％病变逆转趋向于正常。结果表明，低频脉冲电刺激可能通过激活癌前细胞的电化学、电生理变化，改善微循环，提高局部免疫功能，从而发挥对口腔癌前病变的阻断作用。
In this study, oral precancerous lesions of animal models, from in vivo photographic, histological and microvascular and so on, the role of low-frequency pulse electrical stimulation in oral precancerous lesions were observed, the blank control group visible mass production of tumor tissue, 100% lesions of cancer . Low-frequency pulsed electrical stimulation of tumor formation is rare, 33.3% of lesions reversed to normal. The results showed that low-frequency pulsed electrical stimulation could block the precancerous lesions of oral cavity by activating the electrochemical and electrophysiological changes of precancerous cells, improving microcirculation and enhancing local immune function.