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目的观察白芨灌胃在预防中枢性应激性溃疡中的作用。方法将186例重型颅脑外伤或脑血管意外患者随机分为观察组和对照组,各93例。两组患者均予以治疗原发病、脱水、补液及支持、对症治疗。对照组在此基础上使用奥美拉唑注射液静脉注射;观察组在对照组治疗的基础上使用白芨粉从鼻饲管内注入治疗,疗程为1周。观察并统计1周内两组患者中枢性应激性溃疡发生率。结果 1周内观察组中枢性应激性溃疡发生率为9.6%,低于对照组的16.1%,差异有统计学意义(P<0.05)。结论白芨灌胃可能对中枢性应激性溃疡有预防作用。
Objective To observe the role of Baizhu gavage in preventing central stress ulcer. Methods A total of 186 patients with severe traumatic brain injury or cerebrovascular accident were randomly divided into observation group and control group, with 93 cases in each group. Two groups of patients are treated primary disease, dehydration, fluid replacement and support, symptomatic treatment. The control group was treated with omeprazole injection by intravenous injection on the basis of this. The observation group was treated with white powder from the feeding tube on the basis of the control group for one week. The incidence of central stress ulcer in both groups within 1 week was observed and statistically analyzed. Results The incidence of central stress ulcer in the observation group within one week was 9.6%, which was lower than 16.1% in the control group (P <0.05). Conclusion Baizhu gavage may have a preventive effect on central stress ulcer.