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利用幽门螺杆菌具有高活性尿素酶分解尿素的特性作１３Ｃ－尿素呼气试验检测胃十二指肠疾病６０例，随机分为３组，每组２０例，分别用１３Ｃ尿素１００ｍｇ、５０ｍｇ和２５ｍｇ进行检测，结果均可判断ＨＰ感染，三者无明显差别。６０例中ＨＰ阳性３７例，ＨＰ阴性２３例。同时，作胃镜活检组织切片、快速尿素酶试验和培养。计算出１３Ｃ尿素呼气试验的敏感性１００％，特异性为９５．８％。我们认为用１３Ｃ－尿素２５ｍｇ或０．５ｍｇ／ｋｇ作呼气试验效果良好，可大大减少成本费的开支。本法系简单非侵入性检测ＨＰ感染的好方法，对药物筛选及流行病学的研究很有价值
The use of high activity of Helicobacter pylori urease decomposition of urea for 13C-urea breath test for gastroduodenal disease in 60 cases were randomly divided into 3 groups of 20 cases, respectively, with 13C urea 100mg, 50mg and 25mg for testing, the results can be judged HP infection, no significant difference between the three. Among the 60 cases, 37 were positive for HP and 23 were negative for HP. At the same time, biopsies for gastroscopy sections, rapid urease test and culture. Calculated 13 C urea breath test sensitivity of 100%, specificity of 95.8%. We think that 13C-urea 25mg or 0.5mg / kg breath test for good results, can greatly reduce costs and expenses. This is a simple and noninvasive method for detecting HP infection that is valuable for drug screening and epidemiological studies