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对于一些需要安装永久起搏器的患者来讲,由于易于固定,起搏阈值低等优点,右心室起搏常将起搏电极置于心尖部,但长期随访发现,心尖部起搏可改变心室激动顺序,导致心室收缩不同步,造成二尖瓣反流、心房颤动和心功能不全。研究发现右室流出道起搏对左室功能的保护较右室心尖部起搏有利,由于右室流出道起搏靠近His束,电活动近似正常生理状态,可使左右心室电-机械活动更协调,从而抑制心室重构并保护心功能,因此,右室流出道起搏是替代右室心尖部起搏的较好选择。
For patients with permanent pacemakers, right ventricular pacing often places the pacing electrode at the apical part because of its ease of fixation and low pacing threshold. However, long-term follow-up has shown that apical pacing can change the ventricular Excited sequence, leading to ventricular contraction is not synchronized, resulting in mitral regurgitation, atrial fibrillation and cardiac insufficiency. Study found that right ventricular outflow tract pacing protection of left ventricular function than right atrial apical pacing is beneficial because right ventricular outflow tract pacing close to the His beam, electrical activity similar to normal physiological conditions, left and right ventricular electrical - mechanical activity more Coordination, thereby inhibiting ventricular remodeling and protection of cardiac function, therefore, right ventricular outflow tract pacing is a better alternative to right ventricular apex pacing.