论文部分内容阅读
目的 探讨三维适形放射治疗配合化疗治疗非小细胞肺癌 (NSCLC)的疗效。方法 83例NSCLC中鳞癌 50例、腺癌 30例、腺鳞癌 3例。全部患者放射治疗期间均用EP方案 (顺铂 1 0 0mg/m2 第一天、依托泊甙 1 0 0mg/m2 第一至三天 )化疗 2～ 3个周期 ,每 4周为1个周期 ;同时行三维适形常规分割放射治疗总量 60～ 68Gy、5～ 6周完成。 结果 83例近期疗效观察发现 ,2 2例完全缓解 (CR) ,32例部分缓解 (PR) ,2 1例稳定 (NS) ,8例进展 (PD)。肿瘤总有效率 (CR +PR)为 79.1 %。 1 ,2 ,3年生存率分别为 75 .2 %、53 .2 %、35 .4 %。结论 三维适形常规分割照射配合化疗治疗NSCLC有较好的疗效 ,更远期的疗效尚待进一步观察
Objective To investigate the efficacy of three-dimensional conformal radiotherapy combined with chemotherapy in the treatment of non-small cell lung cancer (NSCLC). Methods Fifty cases of squamous cell carcinoma in 83 cases of NSCLC, 30 cases of adenocarcinoma and 3 cases of adenosquamous carcinoma. All patients were treated with EP regimen (first day of cisplatin 100 mg / m2, first to third days of etoposide 100 mg / m2) for 2 to 3 cycles and once every 4 weeks during radiotherapy. Simultaneous three-dimensional conformal radiotherapy for conventional total 60 ~ 68Gy, 5 to 6 weeks to complete. Results A total of 83 patients with complete remission (CR), 32 with partial remission (PR), 21 with stable (NS) and 8 with progress (PD) were observed in 83 patients. The total tumor response rate (CR + PR) was 79.1%. The 1, 2, 3 year survival rates were 75.2%, 53.2% and 35.4% respectively. Conclusion Three-dimensional conformal radiotherapy combined with chemotherapy in the treatment of NSCLC has better curative effect, the more long-term curative effect remains to be further observed