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目的 :探讨硫普罗宁治疗慢性肝炎的临床疗效。方法:6 0例慢性肝炎患者随机分为硫普罗宁组和甘利欣组 ,治疗 2周 ,观察 2组的临床表现、肝功能的变化和不良反应的发生情况。 结果 :硫普罗宁组和甘利欣组的治疗总有效率分别为 90 %、93% (χ2 =0 .2 18,P >0 .0 5 ) ;治疗 2周后 ,硫普罗宁组肝功能有所改善 ,血清白蛋白升高 ,与甘利欣组比较差异有统计学意义 (F =9.0 70 ,P <0 .0 0 1) ;2组未发生严重不良反应。结论 :硫普罗宁是治疗慢性肝炎安全有效的药物。
Objective: To investigate the clinical efficacy of tiopronin in the treatment of chronic hepatitis. Methods: Sixty patients with chronic hepatitis were randomly divided into two groups: tiopronin group and salmeterol group for 2 weeks. The clinical manifestations, liver function changes and adverse reactions of the two groups were observed. Results: The total effective rates of treatment with tiopronin and marxan were 90% and 93%, respectively (χ2 = 0.22, P> 0.05). After 2 weeks of treatment, the liver function of the tiopronin group was Improved, serum albumin increased, compared with the Glycyrrhiza group was statistically significant (F = 9.070, P <0.001); two groups did not occur serious adverse reactions. Conclusion: Tiopronin is a safe and effective drug for the treatment of chronic hepatitis.