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目的:探讨容量管理对腹部外伤并急性呼吸窘迫综合症(ARDS)肺保护作用。方法103例腹部外伤并 ARDS患者分液体管理组和对照组,脉搏指示连续心输出量监测(PiCCO)心输出量(CO)、心指数(CI)、血管外肺水(EVLWI)指导液体管理,测定肺灌洗液白介素-6浓度(IL-6),记录呼吸机参数、动脉血气分析评价肺功能。结果液体管理组动脉氧分压(PaO2)明显提高(P<0.05),EVLWI、IL-6、肺泡-动脉氧分压差(P(A-a)O2)明显下降(P<0.05),呼吸机支持力度下降(P<0.05),肺功能改善。结论容量管理可保护肺功能,与降低炎症、改善氧和等有关。“,”Objective Discuss capacity management on the abdomen injury and acute respiratory distress syndrome lung protection. Methods 103 cases abdominal trauma complicated with acute respiratory distress syndrome were randomly divided into liquid management group and control group, PiCCO monitored CO, CI, EVLWI guidanced liquid management, measuremented bronchofiberscope lung IL-6 concentration, recorded breathing machine parameters, monitored arterial blood gas analysis, evaluatied pulmonary recovery. Results liquid management group arterial blood gas oxygen partial pressure (P<0.05),EVLWI,IL-6 and P(A-a)O2 declined(P<0.05),ventilaor suppored decrease(P<0.05),improved lung function. Conclusions Liquid negative balance can protected pulmonary function,reduced inflammation, improved oxygen.