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本文报告一例贤移植存活1年零50天的尸体解剖及微生物学检查材料。病理形态学所见主要是亚急性肝黄萎缩。死亡原因是白色念珠菌性败血症和急性出血性坏死性胰腺炎。肾组织在电子显微镜下呈现可能是慢性排斥的早期形态改变。作者认为肝脏病变很可能是在硫唑嘌呤损害的基础上合并病毒感染所致。提出合理应用免疫抑制药物,使既能恰当对抗排斥,又能避免感染和胰腺炎的发生,是今后需要加以研究解决的重要课题。
This article reports an example of a cadavers autopsy and microbiology material that survived 1 year and 50 days. Histopathology is mainly seen in subacute liver atrophy. Causes of death are Candida albicans sepsis and acute hemorrhagic necrotizing pancreatitis. Renal tissue under electron microscopy presents an early morphological change that may be chronic rejection. The authors believe that liver disease is likely due to azathioprine damage combined with viral infection. The reasonable application of immunosuppressive drugs to make both appropriate anti-rejection, but also to avoid the occurrence of infection and pancreatitis is an important issue that needs to be studied and solved in the future.