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应用微量细胞毒试验方法,对30例尖锐湿疣患者及20例健康女性(作为对照组),进行T淋巴细胞亚群测定。结果提示:尖锐湿疣患者OKT_3值(63.4±4.9%)、OKT_4值(37.5±4.5%)分别明显低于对照组OKT_3值(67.5±5.1%)、OKT_4值(43.9±4.8%)(P<0.01);尖锐湿疣患者T_4/T_8细胞比值(1.25±0.20%)明显低于对照组(1.55±0.28%)(P<0.01)。可能是由于病毒的感染,导致了尖锐湿疣患者机体内细胞免疫功能调节的紊乱。认为OKT系细胞检测可以作为了解该病人机体免疫功能的一个有价值指标。
T lymphocyte subsets were measured in 30 patients with condyloma acuminatum and 20 healthy women (control group) by using the method of micro-cytotoxicity test. The results showed that OKT_3 (63.4 ± 4.9%) and OKT_4 (37.5 ± 4.5%) in patients with condyloma acuminatum were significantly lower than those in control group (67.5 ± 5.1%, OKT_4, 43.9 ± 4.8% ). The ratio of T 4 / T 8 cells in patients with condyloma acuminatum (1.25 ± 0.20%) was significantly lower than that in control group (1.55 ± 0.28%) (P <0.01). May be due to the virus infection, leading to condyloma acuminatum in patients with the regulation of cellular immune function disorder. OKT line of cells that can be used as a test of the patient’s immune function of a valuable indicator.