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目的 :探讨保妇康栓和聚甲酚磺醛栓治疗宫颈癌患者术后阴道上皮内瘤变的临床疗效。方法 :以2010年1月-2015年1月在我院接受治疗的86例宫颈癌患者术后阴道上皮内瘤变患者为研究对象,采用计算机法进行随机分为治疗组(80)和对照组(60)。治疗组行CO_2激光联合保妇康栓治疗,对照组行CO_2激光联合聚甲酚磺醛栓治疗,观察比较2组患者的临床效果。结果 :治疗后,治疗组与对照组治疗的总有效率分别为97.50%和88.33%,组间差别比较具有统计学意义。治疗后,治疗组与对照组VAIN的治愈率分别为93.68%和81.46%,组间差别比较具有统计学意义。治疗后,治疗组与对照组HPV清除率分别为78.66%和61.38%,组间差别比较具有统计学意义。治疗过程中两组均没有严重不良反应情况发生。结论 :CO_2激光联合保妇康栓治疗宫颈癌术后高危HPV感染VAIN具有较高的VAIN的治愈率和HPV清除率,值得临床推广应用。
Objective: To investigate the clinical effects of Baofukang Suppository and Polypresol Sulphide suppository in the treatment of postoperative vaginal intraepithelial neoplasia in patients with cervical cancer. Methods: From January 2010 to January 2015 in our hospital for treatment of 86 cases of cervical cancer patients with intravaginal intraepithelial neoplasia as the research object, using computerized method were randomly divided into treatment group (80) and control group (60). The CO_2 laser combined with Baofukang suppository was used in the treatment group and CO_2 laser combined with the p-cresol sulphide suppository in the control group. The clinical effects of the two groups were observed and compared. Results: After treatment, the total effective rates of the treatment group and the control group were 97.50% and 88.33%, respectively. The differences between the two groups were statistically significant. After treatment, the cure rates of VAIN in treatment group and control group were 93.68% and 81.46%, respectively. The difference between the two groups was statistically significant. After treatment, the HPV clearance rates of the treatment group and the control group were 78.66% and 61.38%, respectively. The differences between the two groups were statistically significant. During the course of treatment, no serious adverse reactions occurred in both groups. Conclusion: CO_2 laser combined with Baofukang Suppository for the treatment of high risk HPV infection after cervical cancer VAIN has a higher VAIN cure rate and HPV clearance rate, worthy of clinical application.