论文部分内容阅读
目的:探讨血清糖类抗原125(carbohydrate antigen 125,CA125)水平对卵巢子宫内膜异位囊肿的临床诊断价值。方法:选择2003年1月~2012年12月的卵巢子宫内膜异位囊肿患者230例、卵巢良性囊肿患者50例以及门诊体检健康妇女50例(正常对照组),应用电化学发光免疫法分别测定和分析血清CA125水平。结果:卵巢子宫内膜异位囊肿组的血清CA125水平为(88.32±64.89)U/ml,明显高于卵巢良性囊肿组的(25.74±19.04)U/ml和正常对照组的(14.63±6.58)U/ml(t=4.012,P<0.05);卵巢子宫内膜异位囊肿组和卵巢良性囊肿组检测阳性率分别为80.43%(185例)和16.00%(8例),同正常对照组阳性检出率比较均具有统计学意义(P<0.05),并且卵巢子宫内膜异位囊肿组检测阳性率明显高于卵巢良性囊肿组(t=6.129,P<0.05);随着病情分期的增加,230例卵巢子宫内膜异位囊肿患者血清CA125水平具有增高趋势(r=0.910,P<0.05)。结论:血清CA125水平检测对卵巢子宫内膜异位囊肿的诊断具有一定的价值,并且其值随着病情程度的增加而升高,可作为一种非创伤性的辅助检查方法。
Objective: To investigate the clinical value of serum carbohydrate antigen 125 (CA125) in the diagnosis of ovarian endometriosis. Methods: From January 2003 to December 2012, 230 cases of ovarian endometriosis, 50 cases of benign ovarian cysts and 50 healthy women in outpatient examination (control group) were selected. Electrochemiluminescence immunoassay Serum CA125 levels were measured and analyzed. Results: Serum CA125 level in ovarian endometriotic cyst group was (88.32 ± 64.89) U / ml, which was significantly higher than that in benign ovarian cyst group (25.74 ± 19.04) U / ml and normal control group (14.63 ± 6.58) U / ml (t = 4.012, P <0.05). The positive rates of ovarian endometriosis group and benign ovarian cyst group were 80.43% (185 cases) and 16.00% (8 cases) (P <0.05), and the positive rate of ovarian endometriosis was significantly higher than that of benign ovarian cysts (t = 6.129, P <0.05). With the increase of disease stage The serum level of CA125 in 230 patients with ovarian endometriosis increased (r = 0.910, P <0.05). Conclusion: The detection of serum CA125 levels has some value in the diagnosis of ovarian endometriosis cysts, and its value increases with the severity of the disease, which can be used as a non-invasive auxiliary examination.