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目的探讨门诊处方抗菌药物的应用情况。方法选取2014年1—12月江苏省南通市肿瘤医院门诊西药房3650张处方作为研究对象,对其使用药物名称、用法、用量、配伍、联合用药等情况进行统计分析。结果 3650张处方中抗菌药物处方1180张,占32.3%;抗菌药物联合应用情况:单一使用抗菌药物82.2%,二联17.5%,三联及以上0.3%;抗菌药物给药途径:口服57.6%,静脉滴注29.7%,肌内注射6.8%,外用5.9%;抗菌药物种类:共应用6种28种类抗菌药物,以头孢菌素类最多,其次为氟喹诺酮类297张;1180张抗菌药物处方中,不合理使用抗菌药物60张,占5.1%,包括用无指征应用抗菌药物27张,用法不合理15张,药物联用过多10张,配伍不当8张。结论门诊抗菌药物使用基本符合抗菌药物使用原则,但也存在不合理使用情况,需提高医师合理用药意识水平、完善抗菌药物应用相关管理办法、实施动态监测、抽查点评门诊医师处方、分线使用抗菌药物。
Objective To explore the application of prescription antibacterials in clinic. Methods From January to December 2014, 3650 prescriptions of outpatient western pharmacy in Nantong Tumor Hospital of Jiangsu Province were selected as the research object, and the statistical analysis was conducted on the names, usage, dosage, compatibility and combination of the drugs. Results Among the 3650 prescriptions, 1180 were antibiotic prescriptions, accounting for 32.3%. Antibacterials were used in combination: 82.2% of single antibiotics, 17.5% of second drugs and 0.3% of triple and above antibiotics; 57.6% of oral antibiotics were administered intravenously 29.7% instillation, 6.8% in intramuscular injection, and 5.9% in external use. Antibacterials: A total of 6 kinds of 28 kinds of antibacterials were used, of which cephalosporins were the most, followed by fluoroquinolones 297; among 1180 antibacterials, The unreasonable use of antimicrobial drugs 60, accounting for 5.1%, including the use of anti-bacterial drugs without indications 27, irrational use of 15, drug combination with too much 10, improper compatibility 8. Conclusions The use of antimicrobial drugs in outpatient clinics basically conforms to the principle of using antimicrobial drugs, but there are also unreasonable use cases. It is necessary to improve physicians’ sense of reasonable drug use, improve management methods of antimicrobial drug application, carry out dynamic monitoring, spot check clinician prescriptions, drug.