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目的 通过对 1 60 5例老年多器官功能衰竭 (MOFE)患者发病危险因素和临床特征的分析 ,为临床早期诊断、治疗和预防MOFE提供线索。方法 应用回顾性调查的方法。结果 99%MOFE的患者发病前患有 1种以上的基础疾病。MOFE的发病诱因以感染最为多见 ,其中肺部感染最多 ,占 73 .1 % ,首发衰竭的器官以肺居于首位 ,在衰竭器官的类型中 ,血液和肾功能衰竭是MOFE患者死亡的重要危险因素 (OR值分别为 2 .73和 3 .0 0 )。结论 在大多数情况下 ,肺可能是MOFE的启动器官 ;防止呼吸衰竭的发生 ,可能能降低MOFE的发生率 ;在MOFE的治疗中 ,防止肾功能衰竭的发生 ,可能能降低MOFE的死亡率
Objective To analyze the risk factors and clinical features of 1 605 elderly patients with multiple organ failure (MOFE) and provide clues for early diagnosis, treatment and prevention of MOFE. Methods The method of retrospective investigation was used. Results 99% of patients with MOFE had more than one underlying disease prior to onset. The predisposing factors for MOFE were the most common infections, with the highest number of pulmonary infections, accounting for 73.1%. The first failure occurred in the organs of the lungs. In the type of failing organs, blood and renal failure were important risk of death in MOFE patients Factors (OR = 2.73 and 3.0, respectively). Conclusions Lung may be the initiating organ of MOFE in most cases; preventing the occurrence of respiratory failure may reduce the incidence of MOFE; in the treatment of MOFE, the prevention of renal failure may reduce the mortality of MOFE