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目的:探讨早发型重度子病前期(EOSP)孕妇实施期待治疗过程中发生不良妊娠结局的危险因素。方法:回顾性分析2007年1月~2012年1月该院收治103例经期待治疗的EOSP孕妇的临床资料,按照有无孕妇严重并发症的发生分为不良妊娠结局组与对照组,分别比较两组患者的一般临床情况及各项检验指标。采用多因素Logistic回归分析不良妊娠结局的危险因素。结果:103例EOSP期待治疗中,28例孕妇出现严重并发症,发生率为28/103(27.18%)。经Logistic多因素回归分析,发病孕周(以30周为界)、分娩孕周(以32周为界)是孕妇严重并发症发生的独立危险因素。结论:EOSP期待治疗中需严密监护,发病孕周不足30周,分娩孕周小于32周孕妇严重并发症的发生显著增加。
Objective: To explore the risk factors of adverse pregnancy outcome in expectant treatment of early onset severe pre-eclampsia (EOSP). Methods: A retrospective analysis of 103 cases of EOSP expectantly treated in our hospital from January 2007 to January 2012 was performed. According to the presence or absence of serious complications of pregnant women, the patients were divided into the adverse pregnancy outcome group and the control group, respectively Two groups of patients in general clinical conditions and various test indicators. Multivariate logistic regression analysis was used to analyze the risk factors of adverse pregnancy outcome. Results: Among the 103 cases of EOSP expectant treatment, 28 cases of pregnant women had serious complications, the incidence was 28/103 (27.18%). Logistic regression analysis showed that gestational weeks (bounded by 30 weeks) and gestational weeks (bounded by 32 weeks) were independent risk factors for serious complications in pregnant women. Conclusion: EOSP is expected to be closely monitored during treatment. The gestational age is less than 30 weeks, and the incidence of serious complications of pregnant women with gestational age less than 32 weeks is significantly increased.