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国外大量临床试验正在评价小剂量阿司匹林预防先兆子痫和胎儿生长迟缓的效果。复习世界文献,用小剂量阿司匹林治疗300多例妊娠,无大的不利后果。然而在更多结论性证据出现前,妊娠期不要无选择的使用任意剂量的阿司匹林。为了防止致畸的可能性,阿司匹林的应用在孕13周后开始。这些病人的监护应包括:出血的先兆症状和体征、胎儿生长和羊水连续超声检查,连续胎儿心电图检查和新生儿出血并发症的评价。
A large number of foreign clinical trials are evaluating the effect of low-dose aspirin to prevent pre-eclampsia and fetal growth retardation. Review of the world literature, with a small dose of aspirin treatment of more than 300 cases of pregnancy, no major adverse consequences. However, before more conclusive evidence appears, use no dosage of aspirin during pregnancy. In order to prevent the possibility of teratogenicity, the application of aspirin begins after 13 weeks of gestation. Monitoring of these patients should include: aura symptoms and signs of bleeding, fetal growth and continuous amniotic fluid ultrasound examination, continuous fetal electrocardiogram and neonatal bleeding complications.