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对比研究了芦荟大黄素和芦荟大黄素锌配合物体外抗氧化活性。以Fenton反应产生羟自由基,邻苯三酚自氧化反应产生超氧阴离子自由基,二苯代苦味肼(DPPH.)自由基为实验模型,采用紫外可见分光光度法,首次测定芦荟大黄素锌配合物对超氧阴离子、羟自由基、DPPH.自由基的清除作用。结果表明,金属锌离子与芦荟大黄素具有协同抗氧化作用。
In vitro antioxidant activity of aloe-emodin and aloe-emodin zinc complexes was compared. Hydroxyl radical was generated by Fenton reaction, superoxide anion radical was produced by autoxidation of pyrogallol, and DPPH radical was used as experimental model. UV-visible spectrophotometry was used to determine aloe-emodin zinc The scavenging effect of the complex on superoxide anion, hydroxyl radical and DPPH radical. The results show that zinc metal ions and aloe-emodin synergistic antioxidant effect.