Development of artemisinin drugs in the treatment of autoimmune diseases

来源 :Science Bulletin | 被引量 : 0次 | 上传用户:andacaizheng
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Artemisinin drugs are a family of sesquiterpene trioxane lactone agents originally derived from Artemisia annua L. Due to the big victory in the antimalarial battle,the 2015 Nobel Prize goes to the discoverer of artemisininbased therapy for malaria. Beyond antimalaria, artemisinin and its derivatives are also being investigated in diseases like schistosomiasis, viral infection, cancers and inflammation. Over the past decades, the anti-inflammatory and immunomodulatory effects of artemisinin drugs have been comprehensively studied. In this article, we will briefly describe the development of artemisinin drugs, especially novel artemisinin derivatives, in the treatment of autoimmune diseases. Artemisinin drugs are a family of sesquiterpene trioxane lactone agents originally derived from Artemisia annua L. Due to the big victory in the antimalarial battle, the 2015 Nobel Prize goes to the discoverer of artemisininbased therapy for malaria. Beyond antimalaria, artemisinin and its derivatives are also Over the past decades, the anti-inflammatory and immunomodulatory effects of artemisinin drugs have been comprehensively studied. In this article, we will briefly describe the development of artemisinin drugs, especially novel artemisinin derivatives, in the treatment of autoimmune diseases.
其他文献
本文利用微型计算机和数值模拟技术,模拟了6105柴油机曲轴的原始工艺及改进工艺后的凝固过程,预测出铸件中收缩缺陷位置与实际情况相吻合。按改进的工艺方案进行生产,使曲轴铸件缩孔
(一)在当代民族声乐教学中引进地方民间演唱风格的意义近年来,不少有识之士对当代民族声乐歌坛上日益趋同的现象进行过反思。指出在学院派的民族声乐教学中,我们在注重方法的
This paper reports that the GaN thin films with Ga-polarity and high quality were grown by radio-frequency molecular beam epitaxy on sapphire (0001) substrate w
观察心达康对心绞痛患者甲襞微循环(NMC)的影响对88例心绞痛患者(男性56例,女性32例,年龄52±8岁)给予心达康15mg/日,3/日,口服,8周为一疗程,采用WX—6型多部位微循环仪,于服药前3日内及服药8周后分别查NMC,NMC多项指标
约瑟夫·列维涅(Josef Lhevinne)俄罗斯钢琴家,教师J.列维涅1874年生于莫斯科,1944年于纽约去世。列维涅4岁开始学钢琴,12岁进入莫斯科音乐学院,师从萨冯诺夫,同时有塔涅耶夫
对MKJ507低氢焊条在保证其具有良好的焊接工艺性能的同时怎样提高韧性进行了研究。通过提高熔渣的碱度、控制合金元素之间的匹配、加入稀土元素和微量元素Ti等技术途径,成功地研制出高
酰胺咪嗪(Carbamazepine)又称卡马西平是临床常用抗癫痫药。目前检测的方法有比色法、紫外法、薄层色谱法、液相色谱法、气相色谱法等。本文经过比较重新选用气相色谱的内标
There are great differences in biomarks between Cambrian oil and Middle-Upper Ordovician oil. In this stuty, the authors analyzed 40 oils found in Lunnan area b
我国研制成功人工虎骨粉继人工麝香研制成功之后,我国在人工虎骨的研究上又传捷报。中国药品生物制品检定所牵头研制的人工虎骨粉,经检测在药理、毒理及安全性上均与天然虎骨相
随着我国经济的快速发展,真空技术及产品的应用领域不断扩大,企业对真空技术及基础知识的需求也越来越迫切。为提高企业员工的整体素质和管理水平,实施持续、全面的继续教育