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目的:探讨强离子隙（strong ion gap，SIG）对急性百草枯中毒患者预后的评估价值研究。方法:回顾性分析72例急性百草枯中毒患者，按预后分为生存组(18例)和死亡组（54例），并比较中毒早期SIG、阴离子隙（anion gap，AG）、pH、HCOn 3-、乳酸等酸碱指标水平，并建立ROC曲线评估各指标对百草枯中毒患者死亡预后的诊断价值。n 结果:两组间SIG、AG、HCO3n -、乳酸水平均差异有统计学意义（n P0.05）；各检测指标ROC曲线下面积（area under curve，AUC）比较，SIG（0.956）>AG（0.917）>乳酸（0.778）>HCO3n -（0.635）>pH（0.437）；SIG的Youden指数最高（0.60），大于AG（0.321）、乳酸（0.113)） 。n 结论:与其他酸碱失衡指标相比SIG对急性百草枯中毒患者有较好的预后价值。“,”Objective:To investigate the prognostic value of strong ion gap (SIG) in acute paraquat (PQ) poisoning.Methods:Seventy-two PQ poisoning cases were enrolled into a retrospective analysis, which were divided into 2 groups, survival group (n n=18) and death group (n n=54). The levels of SIG, anion gap (AG),pH, HCOn 3-, and lactic acid were compared between the two groups. ROC analysis was used to evaluate the prognostic value of these indexes in PQ poisoning patients.n Results:The levels of SIG, AG, HCOn 3- and lactic acid were significantly different in the survival group and death group (n P AG (0.917) > lactic acid (0.778) > HCO n 3- (0.635) > pH (0.437). The Youden indexes were as follows: SIG (0.60) > AG (0.321) > lactic acid (0.113).n Conclusions:SIG shows a better prognostic value in PQ poisoning compared to other acid-base imbalance indexes.