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近30年来,随着新辅助化疗的开展和完善,骨肉瘤治愈率明显提高[1]。本院收治儿童骨肉瘤1例,采用新辅助化疗,现综合国内外文献,对该治疗方法作一回顾和总结。1病例报告患儿女,5岁4个月。因左膝部疼痛半年、加重2 d于2007年10月10日入院,无外伤史。体检:双下肢不等长,左下肢较右侧长2 cm,左膝部肿胀,肿块周围界限不清,伴压痛,膝关节活动自如。左膝X线片示:较大溶骨性破坏,交界处有硬化骨;膝关节MR平扫:左股骨下段干骺端左侧有处40 mm×32 mm骨质破坏,异常信号区,病灶未突破骨骺板,
In the past 30 years, with the development and improvement of neoadjuvant chemotherapy, the cure rate of osteosarcoma was significantly increased [1]. This hospital admitted to children with osteosarcoma in 1 case, the use of neoadjuvant chemotherapy, are comprehensive domestic and foreign literature on the treatment for a review and summary. 1 case report Children with children, 5 years old 4 months. Because of left knee pain for six months, increased 2 d on October 10, 2007 admission, no history of trauma. Physical examination: the lower extremities ranged in length, the lower extremities were 2 cm longer than the right extremity, the left knee was swollen, the area around the lumps was unclear, tenderness was present, and the knee joint was free to move. Left knee X-ray showed: greater osteolytic destruction, the junction of sclerotic bone; knee MR plain: the left femoral left metaphyseal left there 40mm × 32 mm bone destruction, abnormal signal area, the lesion Did not break the epiphyseal plate,