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目的探讨采用肝动脉灌注化疗预防肝癌术后复发的效果。材料和方法共１９２例肝癌根治术后患者，预防组１０４例，接受肝动脉灌注化疗５８６次，平均５．６次，最多者１０次；对照组８８例，未接受灌注化疗。结果两组术后１、３、５年复发率分别为２８．８６％（３０／１０４）、４５．３３％（３４／７５）、７０％（２８／４０）和５１．１４％（４５／８８）、６５．０８％（４１／６３）、９０．３８％（４７／５２），经卡方检验差异显著（Ｐ＜０．０５），预防组复发率也低于文献报道。结论预防性肝动脉灌注化疗能有效降低肝癌术后复发率。
Objective To investigate the effect of hepatic arterial infusion chemotherapy in the prevention of recurrence of liver cancer. Materials and Methods A total of 192 patients with hepatocellular carcinoma after radical resection and 104 patients in the preventive group received 586 hepatic arterial infusion chemotherapy with an average of 5.6 and a maximum of 10; 88 patients in the control group did not receive infusion chemotherapy. Results The recurrence rates of the two groups at 1, 3, and 5 years after operation were 28.86% (30/104), 45.33% (34/75), 70% (28/40), and 51.14% (45/ 88), 65.08% (41/63), 90.38% (47/52), significantly different (p<0.05) by chi-square test, the recurrence rate of prevention group was also lower than that reported in the literature. Conclusion Prophylactic hepatic arterial infusion chemotherapy can effectively reduce the recurrence rate of liver cancer after operation.