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尿激酶(UK)是治疗急性血栓栓塞疾病效果较好的溶栓药物。我们于1988年10月～1990年3月,应用国产 UK 治疗急性动脉栓塞20例,取得了较好的疗效。现将本组资料进行总结,并作简要讨论。1.治疗方法 UK 首剂量是10～30万 u,以后渐减量,静脉点滴或静脉点滴与动脉注射同时给药。平均总量为172.75万 u。此外,还常规静点小分子右旋糖酐500ml。部分病例给小剂量肝素,口服潘生丁、消炎痛、阿司匹林、安定。本组没有出现 UK 引起的出血等副作用。
Urokinase (UK) is a thrombolytic agent for the treatment of acute thromboembolic diseases. We in October 1988 ~ March 1990, the application of domestic UK treatment of acute arterial embolism in 20 cases, and achieved good results. Now this group is summarized, and make a brief discussion. 1. The first dose of UK treatment is 10 to 30 million u, after decreasing gradually, intravenous drip or intravenous drip and arterial injection at the same time. The average total amount is 1,727,500 u. In addition, the conventional static small molecule dextran 500ml. Some cases to low-dose heparin, oral dipyridamole, indomethacin, aspirin, stability. This group did not appear to cause bleeding and other UK side effects.