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目的 探讨慢性炎症性脱髓鞘性多发性神经病 (CIDP)的临床特征及有关实验室检测指标的改变。方法 回顾分析 32例CIDP患者的起病形式、临床表现、脑脊液及电生理学检测结果。结果 32例CIDP患者中双下肢起病者占 71.8% ,多为对称性肢体肌力减弱 ;75 %的患者为感觉运动混合型 ;脑脊液检查见 87.5 %的患者出现蛋白 细胞分离 ,93.8%的IgG增高 ;电生理学检查96 .9%患者出现异常 ,包括神经传导潜伏期延长 ,传导速度减慢 ,传导阻滞 ,F波的异常及肌电图 (EMG)异常。结论 对缓慢起病、对称性肢体麻木无力患者 ,应考虑到CIDP可能 ,及时进行脑脊液及电生理学检查。
Objective To investigate the clinical features of chronic inflammatory demyelinating polyneuropathy (CIDP) and related laboratory tests. Methods Retrospective analysis of 32 cases of CIDP patients with the onset form, clinical manifestations, cerebrospinal fluid and electrophysiological test results. Results 32 cases of CIDP patients accounted for 71.8% of patients with both lower extremities, mostly symmetrical limb muscle weakness; 75% of patients with sensory mix; cerebrospinal fluid examination showed 87.5% of patients with protein cell separation, 93.8% of IgG (96.9%) were abnormal in electrophysiological examination, including prolonged nerve conduction latency, slow conduction velocity, conduction block, abnormalities of F wave and abnormal electromyogram (EMG). Conclusions For patients with slow onset and symmetrical limb numbness, CIDP should be taken into account and cerebrospinal fluid and electrophysiological examination should be conducted promptly.