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为探讨小梁切除术中应用丝裂霉素Ｃ（ＭＭＣ）致前房出血的原因。方法：回顾性分析９９例１４２眼原发性青光眼小梁切除术后前房出血的情况，对术中未应用ＭＭＣ与术中巩膜瓣上及巩膜瓣下放置０．３～０．４ｍｇ／ｍｌＭＭＣ４～５分钟，术后前房出血的发生率进行了比较。结果：未应用ＭＭＣ组前房出血的发生率为４．１７％，巩膜瓣上置ＭＭＣ组前房出血的发生率为６．０６％，巩膜瓣下置ＭＭＣ组前房出血的发生率为３７．８４％，明显高于前两组，Ｐ＜０．０１。结论：巩膜瓣下置ＭＭＣ组前房出血的发生率明显增高，可能是ＭＭＣ对睫状体血管内皮细胞损伤的结果。
To investigate the application of mitomycin C (MMC) in trabeculectomy caused by anterior chamber hemorrhage. Methods: A retrospective analysis of 99 cases of 142 cases of primary glaucoma after trabeculectomy in patients with anterior chamber hemorrhage, intraoperative application of MMC and intraoperative scleral flap and scleral flap placed 0.3 ~ 0.4mg / mlMCMC4 ~ 5 minutes, the incidence of postoperative anterior chamber hemorrhage were compared. Results: The incidence of anterior chamber hemorrhage was 4.17% in MMC group, 6.06% in MMC group with scleral flap, and 37 in MMC group .84%, significantly higher than the first two groups, P <0.01. Conclusion: The incidence of hyphema in MMC group under scleral flap is significantly higher than that in MMC group, which may be the result of MMC injury to ciliary body vascular endothelial cells.