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目的总结分析食道癌患者不同术式治疗的效果。方法消化道重建手术治疗的150例食道癌患者为研究对象,根据手术吻合口位置不同分为A组(胸内吻合组)51例、B组(食管床吻合组)49例、C组(颈部吻合组)50例,所有患者手术后持续24 h监测食管腔内pH值,比较分析三组患者治疗效果。结果 A组患者24 h返流总次数、持续5 min以上返流次数、最长返流时间、pH<4总时间、DeMeester评分等观察指标明显高于B组、C组,差异具有统计学意义(P<0.01)。结论食管癌患者不同手术治疗均存在一定程度的食管反流现象,但吻合口越高者术后反流发生率越低,有利于改善患者生活质量。
Objective To summarize and analyze the effect of different surgical treatment of esophageal cancer patients. Methods A total of 150 patients with esophageal cancer undergoing gastrointestinal reconstructive surgery were enrolled in this study. According to the location of the anastomotic anastomosis, 51 patients in group A (intrathoracic anastomosis group), 49 in group B (esophageal anastomosis group), 49 in group C Department of anastomosis group) 50 cases, all patients continued monitoring of esophageal intraluminal pH 24 hours after surgery, the comparative analysis of three groups of patients with treatment. Results The total number of 24 h regurgitation, the number of reflux more than 5 min, the longest regurgitation time, pH <4 total time, DeMeester score and other indexes in group A were significantly higher than those in group B and C, the difference was statistically significant (P <0.01). Conclusions Esophageal cancer patients have some degree of esophageal reflux during different surgical procedures. However, the higher the anastomotic rate is, the lower the incidence of postoperative reflux is, which will help to improve the quality of life of patients.