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目的:探讨曲安奈德玻璃体腔内注射后眼压的改变及影响因素。方法:回顾分析在我院接受玻璃体腔注射4mg曲安奈德治疗的125人125眼其中糖尿病视网膜病变49例,视网膜静脉阻塞56例,老年渗出性黄斑病变20例,平均随访5个月(3～21个月)。术后眼压≥21mmHg定为眼压升高(1mmHg=0.133kPa)。结果:术后36人眼压升高(28.8%),术前眼压平均值为14.69±3.72mmHg(7～31mmHg),术后随访期峰值眼压平均为20.09±758mmHg(9～53mmHg),比术前眼压平均升高5.43mmHg(-9～34mmHg),P<0.001,表明曲安奈德注射后眼压有显著升高。结论:曲安奈德注射后眼压较术前有显著升高;眼压升高大部分发生于术后3个月内,7个月恢复基准水平;术前眼压≥15mmHg者术后眼压升高比例明显增加;年龄偏低者术后眼压升高比例大。不同病因术后眼压升高倾向不同。
Objective: To investigate the changes of intraocular pressure (IOP) and its influencing factors after triamcinolone acetonide intravitreal injection. Methods: A retrospective analysis of 125 patients with 125 eyes treated with intravitreal triamcinolone acetonide in our hospital was retrospectively analyzed. Among them, 49 were diabetic retinopathy, 56 were retinal vein occlusion, 20 were exudative macular degeneration. The average follow-up was 5 months (3 ~ 21 months). Postoperative intraocular pressure ≥ 21mmHg as intraocular pressure (1mmHg = 0.133kPa). Results: The intraocular pressure (IOP) was increased in 36 patients (28.8%) after operation, the mean preoperative IOP was 14.69 ± 3.72mmHg (7 ~ 31mmHg), and the peak IOP was 20.09 ± 758mmHg (9 ~ 53mmHg) An average of 5.43 mmHg (-9 ~ 34 mmHg) higher than preoperative IOP, P <0.001, indicating a significant increase in IOP after triamcinolone acetonide injection. CONCLUSIONS: Intraocular pressure (IOP) after triamcinolone acetonide injection was significantly higher than that before operation. Most of intraocular pressure (IOP) occurred within 3 months after operation and returned to baseline level at 7 months. Intraocular pressure A significant increase in the proportion of high; lower age patients with a large proportion of postoperative intraocular pressure. Different causes of postoperative elevated intraocular pressure tend to be different.