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目的:探讨死胎发生的高危因素。方法:将2007年1月～2010年11月苏州大学附属第一人民医院住院分娩的死胎78例设为病例组,随机抽取同期住院分娩活产156例作为对照组,对两组18个社会及临床因素进行回顾性分析。结果:比较两组的高龄、职业、教育程度、产前检查、孕周、出生体重、胎数、产次、胎膜早破、胎盘早剥、胎儿畸形、母体合并症等指标,差异有统计学意义。Logistic回归分析表明无正规产前检查(OR=3.202,95%CI 3.074～3.548)、低出生体重(OR=0.998,95%CI 0.997～0.999)、无业(OR=1.279,95%CI 1.096～1.804)、胎儿畸形(OR=2.264,95%CI 2.102～2.573)、母体疾病(OR=4.608,95%CI 10.859～24.707)是发生死胎的高危因素。结论:必须加强产前检查,提高产前诊断水平,及时发现早期胎儿畸形,加强对高危孕妇的筛选及重点监护,积极治疗各种妊娠合并症及并发症,减少死胎的发生。
Objective: To investigate the risk factors of stillbirth. Methods: From January 2007 to November 2010, 78 cases of stillbirth admitted to the First People’s Hospital Affiliated to Soochow University were selected as the case group. 156 cases of live births during the same period were randomly selected as the control group. Two groups of 18 social and Clinical factors were retrospectively analyzed. Results: There were statistically significant differences between the two groups in terms of age, occupation, educational level, prenatal examination, gestational age, birth weight, number of fetuses, parity, premature rupture of membranes, abruption of placenta, fetal malformations and maternal complications Significance of learning. Logistic regression analysis showed no prenatal diagnosis (OR = 3.202, 95% CI 3.074-3.548), low birth weight (OR = 0.998, 95% CI 0.997-0.999) ), Fetal malformation (OR = 2.264, 95% CI 2.102-2.573), and maternal disease (OR = 4.608,95% CI 10.859-24.707) were risk factors for stillbirth. Conclusion: Prenatal examination must be strengthened to improve the level of prenatal diagnosis, early detection of early fetal malformations, screening of pregnant women at high risk and intensive monitoring, active treatment of various pregnancy complications and complications, and reduction of stillbirth.