儿童肺动脉高压的诊断及治疗

• 作 者: 张燕宏 王树岩
• 机 构: 首都医科大学附属北京朝阳医院,首都医科大学附属北京朝阳医院 北京 100020,北京 100020
• 出 处: 国外医学(儿科学分册)
• 发表日期: 2002年04期
• 关键词: 肺动脉高压 肺移植 呼吸系统疾病 前列环素 儿科疾病 肝脏疾患 先天性心脏病 潜在疾病 呼吸急促 呼吸困难

肺动脉高压（PH）是儿科疾病（先天性心脏病,肺部疾患,肝脏疾患）常见的合并症,并且是引起死亡的重要因素。PH分为原发性和继发性。发生PH的主要原因为:PH,肺静脉高压,呼吸系统疾病,栓塞性疾病。PH的临床症状不典型,常见胸痛、呼吸困难、呼吸急促以及晕厥等表现。无创性检查方法对诊断PH很重要。对于严重PH的儿童应该进行评价,干预治疗是治疗其潜在疾病。治疗方法包括给予血管扩张剂,长期注射前列环素、内皮素受体阻滞剂和应用一氧化氮,最终可行肺移植。

Pulmonary hypertension (PH) is a common complication of pediatric diseases (congenital heart disease, lung disease, liver disease) and is an important cause of death. PH is divided into primary and secondary. The main reasons for the occurrence of PH: PH, pulmonary hypertension, respiratory diseases, embolic disease. PH clinical symptoms are not typical, common chest pain, difficulty breathing, shortness of breath and fainting performance. Noninvasive methods are important for the diagnosis of PH. For children with severe PH should be evaluated, intervention treatment is the treatment of its underlying disease. Treatment includes vasodilators, long-term injection of prostacyclin, endothelin receptor blocker and the application of nitric oxide, and ultimately feasible lung transplantation.