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目的:研究PCT监测在ICU病房多重耐药感染患者中的临床应用价值。方法:回顾性分析我院在2009年11月至2014年1月间收治的82例ICU病房多重耐药感染患者的临床资料,随机将患者分为两组,对照组采用常规抗生素治疗,观察组在对照组基础上实施PCT监测,比较两组患者抗生素使用与炎性反应情况。结果:观察组抗生素使用时间低于对照组,对比差异显著,具有统计学意义(P<0.05)。观察组C反应蛋白与IL-6均低于对照组,对比存在较大差异,具有统计学意义(P<0.05)。观察组患者在第2、4、8、12天的血清水平均高于对照组,对比具有统计学意义(P<0.05)。结论:PCT监测有利于实现抗生素的合理使用,对于患者预后与治疗具有促进作用,值得推广应用。
Objective: To study the clinical value of PCT monitoring in patients with multiple drug-resistant infections in ICU wards. Methods: The clinical data of 82 ICU ward patients with multiple drug-resistant infections admitted to our hospital from November 2009 to January 2014 were retrospectively analyzed. The patients were randomly divided into two groups. The control group was treated with conventional antibiotics. The observation group On the basis of the control group, the PCT surveillance was performed and the antibiotic use and inflammatory response were compared between the two groups. Results: The antibiotic use time in the observation group was lower than that in the control group, the difference was significant, with statistical significance (P <0.05). The levels of C-reactive protein and IL-6 in the observation group were lower than those in the control group, showing significant differences (P <0.05). The serum level of the observation group was higher than that of the control group on the 2nd, 4th, 8th and 12th days (P <0.05). Conclusion: PCT monitoring is conducive to the rational use of antibiotics and has a promoting effect on the prognosis and treatment of patients, which is worth popularizing and applying.