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目的探讨联合药物治疗及阴茎背神经切断术对原发性早泄患者射精潜伏期、性生活满意度的干预效果及对临床疗效的影响。方法原发性早泄患者分为联合药物组24例和手术治疗组17例。联合药物组给予盐酸舍曲林50mg每日1次口服,复方利多卡因乳膏性交前15分钟阴茎头外用,手术组实施阴茎背神经切断术。4周后,两组应用阴道内射精潜伏期及性生活满意度进行评定,并比较两组临床疗效。结果治疗前两组阴道内射精潜伏期分别为(0.93±0.35)min,(0.91±0.39)min,治疗后分别为(4.27±1.51)min,(4.46±1.65)min,两组治疗后射精潜伏期均显著高于治疗前(P<0.01)。治疗前两组性交满意度分别为(1.39±0.68),(1.31±0.77),治疗后分别为(4.45±0.88),(4.51±1.03)。治疗后1个月两组有效率分别为79.17%,82.35%。两组组间比较均无显著性差异。结论联合药物治疗与阴茎背神经切断术治疗原发性早泄均安全、有效。
Objective To investigate the effect of combined medication and penile dorsal nerve transection on ejaculation latency and sex life satisfaction in patients with primary premature ejaculation and its clinical effect. Methods The patients with primary premature ejaculation were divided into 24 cases in combination group and 17 cases in operation group. The combination group was given sertraline hydrochloride 50mg orally once daily for 15 minutes before oral administration of lidocaine cream and the penis was applied externally. The dorsal penile nerve transection was performed in the operation group. After 4 weeks, the two groups were evaluated by intravaginal ejaculation latency and sexual life satisfaction, and the clinical efficacy was compared between the two groups. Results The latent period of intravaginal ejaculation in the two groups before treatment was (0.93 ± 0.35) min and (0.91 ± 0.39) min respectively, and (4.27 ± 1.51) min and (4.46 ± 1.65) min after treatment respectively Significantly higher than before treatment (P <0.01). The satisfaction satisfaction level of the two groups before treatment was (1.39 ± 0.68) and (1.31 ± 0.77) respectively, and (4.45 ± 0.88) and (4.51 ± 1.03) respectively after treatment. One month after treatment, the effective rates of the two groups were 79.17% and 82.35% respectively. There was no significant difference between the two groups. Conclusions Combination therapy and dorsal penile nerve transection are safe and effective in treating primary premature ejaculation.