多发性阴囊表皮松解性棘皮瘤:继发于外伤?

• 作 者: Banky J.P.ner R.J. Hollowood K. 马慧群
• 机 构: Dermatology Department, Oxford Radcliffe Hospitals, Churchill Hospital, Old Road, Headington, Oxford
• 出 处: 世界核心医学期刊文摘(皮肤病学分册)
• 发表日期: 2005年02期
• 关键词: 阴囊 外伤 继发 文章报道 角蛋白 发育异常 播散性 病因 搔抓 称谓

Epidermolytic hyperkeratosis (EH) is an abnormality of epidermal maturation, most commonly due to mutations in keratins 1 and 10, which may be a congenital or an acquired defect. The term epidermolytic acanthoma was applied to a solitary discrete epidermal proliferation characterized by EH. Subsequently there have been several reports of disseminated epidermolytic acanthomas. We report a rare case of multiple epidermolytic acanthomas localized to the scrotum. With the aetiology of epidermolytic acanthoma unknown, trauma has been postulated as a possible cause. Our patient repetitively scratched his scrotum for 5 years and we believe that this action triggered his multiple scrotal epidermolytic acanthomas.

Epidermolytic hyperkeratosis (EH) is an abnormality of epidermal maturation, most commonly due to mutations in keratins 1 and 10, which may be a congenital or an acquired defect. The term epidermolytic acanthoma was applied to a solitary discrete epidermal movement characterized by EH. There are several reports of disseminated epidermolytic acanthomas. We report a rare case of multiple epidermolytic acanthomas localized to the scrotum. With the aetiology of epidermolytic acanthoma unknown, trauma has been postulated as a possible cause. Our patient repetitively scratched his scrotum for 5 years and we believe that this action triggered his multiple scrotal epidermolytic acanthomas.