论文部分内容阅读
目的探讨亚临床甲状腺功能减退(SCH)对妊娠期糖尿病(GDM)发病及妊娠结局的影响。方法选取2014年1月-2014年12月在邢台市人民医院建档及分娩的孕妇2 466例,分为SCH组285例和对照组2 181例。结果 SCH组糖尿病发病率高于对照组(P<0.01);SCH组TPOAb阳性率、TSH水平高于对照组,差异有统计学意义(均P<0.01),两组FT4水平差异无统计学意义(P>0.05)。依据75 g葡萄糖耐量试验(OGTT)进一步将其分为SCH+GDM组、SCH-OGTT正常组、对照-GDM组及对照-OGTT正常组,SCH+GDM组子痫前期、剖宫产、新生儿窒息、早产流产率均高于其他组。结论 SCH会增加GDM发病,SCH合并GDM增加妊娠不良结局的风险,应注重SCH妊娠妇女血糖监测及控制。
Objective To investigate the effect of subclinical hypothyroidism (SCH) on the incidence of gestational diabetes mellitus (GDM) and pregnancy outcome. Methods Totally 2 466 pregnant women, who were filing and giving birth in Xingtai People’s Hospital from January 2014 to December 2014, were divided into SCH group (285 cases) and control group (2 181 cases). Results The incidence of diabetes mellitus in SCH group was higher than that in control group (P <0.01). The positive rates of TPOAb and TSH in SCH group were higher than those in control group (all P <0.01), and there was no significant difference between the two groups (P> 0.05). According to the 75 g glucose tolerance test (OGTT), they were further divided into SCH + GDM group, SCH-OGTT normal group, control-GDM group and control -OGTT normal group, SCH + GDM group, preeclampsia, cesarean section, Asphyxia, abortion rate were higher than other groups. Conclusion SCH will increase the incidence of GDM, SCH combined GDM increase the risk of adverse pregnancy outcomes should pay attention to SCH pregnant women blood glucose monitoring and control.