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用柠檬酸铝和羟基磷酸喹哌治疗矽肺病人40例，20例病人给安慰剂作为对照，进行了2年6个疗程的治疗对比观察。结果发现两组病人临床症状均有不同程度改善，X线胸片结果表明治疗组37例（有3例因出现合并病未统计）中治疗后有好转与明显好转共4例，占10．81％，1例有进展，而对照组20例中无1例好转，进展与明显进展共5例，占25％，两组比较差异显著（P＜0．05）。用综合疗效评价指标发现两组差异非常显著（P＜0．001）。在治疗期间未发现明显毒副作用，说明用柠檬酸铝和羟基磷酸喹哌联合治疗矽肺的方法是有效而安全的，宜推广应用。
Forty patients with silicosis were treated with aluminum citrate and quinafloxacin, and 20 patients were given placebo as control. Two years of 6 courses of treatment were compared. The results showed that the clinical symptoms of both groups were improved to varying degrees, X-ray findings showed that the treatment group of 37 patients (3 cases due to the occurrence of combined disease did not statistic) after treatment, improvement and significant improvement in a total of 4 cases, accounting for 10.81 %, 1 case progressed, while none of the 20 cases in the control group improved. There were 5 cases (25%) in progress and obvious progress. There was significant difference between the two groups (P <0.05). With the comprehensive evaluation of the efficacy of indicators found that the difference between the two groups was significant (P <0.001). No significant side effects were found during the treatment, indicating that the combination of aluminum citrate and quinpirole phosphate treatment of silicosis is effective and safe and should be widely applied.