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目的:探讨血清降钙素原(procalcitonin,PCT)、血乳酸与小儿危重病例评分的相关性及临床意义。方法:对33例休克患儿入住危重监护病房时立即进行小儿危重病例评分,根据评分分为极危重组(3例)、危重组(14例)、非危重组(16例)。同时检测血清PCT、乳酸,并进行相关性分析。结果:极危重组血清PCT、乳酸水平及病死率均明显高于危重组和非危重组(均P<0.01),而小儿危重病例评分均明显低于其他两组(均P<0.01)。血清PCT、乳酸水平与危重病例评分的相关系数分别为-0.621(P<0.05)和-0.890(P<0.01)。结论:危重监护病房休克患儿血PCT、乳酸水平与小儿危重病例评分呈明显负相关,检测PCT及乳酸对判断预后有重要意义。
Objective: To investigate the correlation and clinical significance of serum procalcitonin (PCT), blood lactate and pediatric critical illness score. Methods: Thirty-three children with critical shock were divided into critically ill group (n = 3), critically ill group (n = 14) and non-critically ill group (n = 16) according to the score immediately after admission to critical care unit. At the same time, serum PCT and lactate were detected and their correlations were analyzed. Results: The levels of serum PCT, lactate and mortality in critically ill patients were significantly higher than those in critically ill patients and non - critically ill patients (all P <0.01). However, the scores of critically ill children were significantly lower than those of the other two groups (all P <0.01). The correlation coefficients of serum PCT, lactic acid levels and critical case scores were -0.621 (P <0.05) and -0.890 (P <0.01), respectively. Conclusion: The levels of serum PCT and lactate in children with critical care unit were negatively correlated with the scores of critical cases in children. The detection of PCT and lactic acid is of great significance in judging prognosis.