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目的通过研究硫糖铝对消化性溃疡涂抹情况,以探讨硫糖铝对消化性溃疡保护作用,为临床用药提供理论依据。方法将24例患者随机分为对照组(慢性浅表性胃炎)和胃溃疡组12例,空腹嚼服硫糖铝。其余24例患者随机分为对照组(慢性浅表性胃炎),十二指肠溃疡组,空腹口服硫糖铝悬液。服药30min后进行胃镜检查,观察硫糖铝对上消化道黏膜涂抹情况。结果与对照组比较,胃溃疡组胃窦部涂抹均匀;十二指肠溃疡组十二指肠球部涂抹均匀。结论硫糖铝向溃疡部位聚集,更好的保护病变处黏膜。
Objective To study the application of sucralfate to peptic ulcer to explore the protective effect of sucralfate on peptic ulcer and provide a theoretical basis for clinical use. Methods Twenty-four patients were randomly divided into control group (chronic superficial gastritis) and gastric ulcer group (n = 12). The remaining 24 patients were randomly divided into control group (chronic superficial gastritis), duodenal ulcer group, fasting oral sucralfate suspension. Gastroscopy after 30min medication to observe the sucralfate mucosa on the upper gastrointestinal smear. Results Compared with the control group, gastric antrum of gastric ulcer group smear evenly; duodenal ulcer group duodenal ball smear evenly. Conclusion sucralfate gathered to the ulcer site, better protection of the lesion mucosa.