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目的 :探讨消化系统肿瘤相关抗原 (CA19 9)对胰腺癌的临床意义及实用价值。方法 :用酶联免疫吸附法 ,对 39例临床确诊的胰腺癌患者术前及术后 2个月进行血清学CA19 9跟踪检测 ,以 6 0名健康献血员作对照。结果 :胰腺癌患者的手术前、后及对照组CA19 9值分别为 48.2± 14.5u/ml、2 4.4± 9.1u/ml和 15 .7± 5 .6u/ml。其敏感性为 89.7% ,特异性 10 0 % ,术前与术后及对照组比较差异有显著性 (P <0 .0 1)。结论 :CA19 9对胰腺癌具有高度特异性 ,它不仅对胰腺癌的辅助诊断 ,而且可对高危人群的普查和筛选有重要意义 ,并可对患者术后进行有效监控。
Objective: To investigate the clinical significance and practical value of digestive system tumor associated antigen (CA19 9) in pancreatic cancer. Methods: Thirty-nine patients with clinically diagnosed pancreatic cancer were enrolled in this study. Serum CA19 9 was detected preoperatively and 2 months after surgery. Sixty healthy blood donors were used as controls. Results: The values of CA19 9 in preoperative, postoperative and control groups of patients with pancreatic cancer were 48.2 ± 14.5u / ml, 24.4 ± 9.1u / ml and 15.7 ± 5.6u / ml, respectively. The sensitivity and specificity were 89.7% and 100% respectively. There was significant difference between preoperative and postoperative and control groups (P <0.01). CONCLUSION: CA19 9 is highly specific for pancreatic cancer. It is not only aided diagnosis of pancreatic cancer, but also important for the screening and screening of high-risk groups. It can also monitor the postoperative patients effectively.