Exercises for Parkinson′s disease

• 出 处: 中华物理医学与康复杂志
• 发表日期: 2017年39期

BACKGROUND AND OBJECTIVE

While short-term exercise may improve health, well-being and function in patients with Parkinson′s disease (PD), there is a lack of evidence of long-term benefits. This study was designed to better understand these benefits.

METHODS

This phase II, randomized, controlled trial included patients with idiopathic PD, who were able to walk at least 100 m. The subjects were randomized to perform exercises or receive handwriting training, twice per week for six months. Exercise included 30 minutes of aerobic training followed by 30 minutes of resistance training. A control group underwent handwriting exercises, using workbooks at home. Outcome measures were performed at baseline, and at three, six and 12 months. The primary outcome measure was the two-minute walk test. Mobility was also assessed using the Timed Up and Go Test, the Nine Hole Peg Test and global motor function assessed using the Motor function assessed using the Motor Examination of the MDS-UPDRS (III).

RESULTS

At 12 months, during the two-minute walk test, the exercise group was able to walk 144.6 m, while the control group walked 137.9 m (P＝0.06). The largest effect was found on the MDS-UPDRS III at 12 months (P<0.05), indicating an improvement in motor symptoms (P<0.05). Small, statistically insignificantly better gains were found in the exercise group than in the control group in improvement in leg power, aerobic capacity and perceived health-related quality of life.

CONCLUSION

This study of patients with Parkinson′s disease suggests that twice weekly aerobic and resistance exercise may improve physical function.