论文部分内容阅读
流行病学资料调查表明，大同市南郊区北村乡近年来恶性肿瘤死亡呈明显的上升趋势，为了探讨癌高发的原因，本文对该地区大气、地面水及居民饮水、蔬菜和人群血清的污染情况进行相关因素的分析调查。结果表明，大气中的苯并（a）芘（Bap）、悬浮颗粒物（TSP）及饮食中硝酸盐、亚硝酸盐均高于非污染区，地面水污染严重。同时该地区居民外周血淋巴细胞微核、畸变核及人群血清铜含量、铜／锌比值均明显高于对照区，差异均非常显著（P＜0．01），并与该地区大气中Bap和TSP、饮食中的硝酸盐和亚硝酸盐成正相关。结果还表明，该地区居民外周血淋巴细胞的非程序DNA合成（UDS）试验的cpm值明显低于对照组，差异非常显著（P＜0.001），并与大气、水源的污染因素成负相关。认为大同市北村乡地区近年来大气、水源的严重污染可能是该地区居民细胞遗传物质损伤及癌发病率增高的重要因素。
Epidemiological data surveys show that the deaths of malignant tumors in Beicun Township, the southern suburb of Datong City, have increased significantly in recent years. In order to investigate the causes of the high incidence of cancer, the pollution of the atmosphere, surface water, drinking water, vegetables, and human serum in the region is discussed in this paper. Analyze relevant factors. The results showed that benzo(a)pyrene (Bap), suspended particulates (TSP), dietary nitrate and nitrite were higher than non-polluted areas, and the surface water pollution was serious. At the same time, peripheral blood lymphocyte micronucleus, aberrant nucleus, and serum copper and copper/zinc ratios of the residents in the area were significantly higher than those in the control area (P<0.01), and were related to Bap in the atmosphere. TSP, dietary nitrate and nitrite are positively correlated. The results also showed that the cpm values of the unprogrammed DNA synthesis (UDS) test of peripheral blood lymphocytes of residents in this area were significantly lower than those of the control group (P<0.001), and were negatively correlated with atmospheric and water pollution factors. It is believed that the serious pollution of the air and water sources in Beicun Township, Datong City in recent years may be an important factor in the increase of cellular genetic material damage and cancer incidence in the residents of the area.