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目的:观察丹参注射液联合复方甘草酸苷治疗慢性乙型肝炎肝功能疗效及安全性。方法:选取2010年12月~2012年12月来我院就诊的慢性乙肝患者54例,将患者分成2组。治疗组28例用丹参注射液联合复方甘草酸苷,对照组26例用还原型谷胱甘肽注射液,2组疗程均为30天,观察患者的肝功能及肝纤维化指标的变化。结果:治疗组对肝功能及肝纤维化指标方面明显优于对照组(P<0.01)。结论:丹参注射液联合复方甘草酸苷联合用药治疗慢性乙型肝炎患方具有良好的抗纤维化疗效。
Objective: To observe the efficacy and safety of Danshen injection combined with compound glycyrrhizin in the treatment of chronic hepatitis B liver function. Methods: 54 patients with chronic hepatitis B who came to our hospital from December 2010 to December 2012 were selected and divided into 2 groups. In the treatment group, 28 cases were treated with Salvia miltiorrhiza injection combined with compound glycyrrhizin, and 26 cases with control group were treated with reduced glutathione injection. The two courses of treatment were 30 days. The changes of liver function and liver fibrosis were observed. Results: The treatment group was significantly better than the control group on liver function and liver fibrosis (P <0.01). Conclusion: Salvia miltiorrhiza injection combined with compound glycyrrhizin in the treatment of patients with chronic hepatitis B has good anti-fibrosis effect.