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肿瘤的发生是由于诱变剂、遗传因素或二者共同作用的结果,不同的研究者均支持这一假说。Atkin提出1号染色体异染色质的量可能与肿瘤发生存在某种关系,并使机体易于产生某些恶性疾病。另一些作者也证实这种观察。有关血液系恶性肿瘤、白血病前期、白血病、骨髓瘤和其它血液病染色体,C带区的分布有显著差别已有报道。本文研究非何杰金氏淋巴瘤(NHL)1、9和16号染色体的异染色质区。 50例新诊断的NHL,年龄8～77岁。取其外周血淋巴细胞培养,研究其1、9和16号染色体的异态性。运用Rapport分类法诊断NHL。随机选取55名健康个体,年龄在1天到45岁,组成对照组。运用BSG技
Tumor development results from mutagens, genetic factors, or both, and is supported by different researchers. Atkin suggested that the amount of chromosome 1 heterochromatin may have a relationship with the occurrence of cancer and make the body prone to certain malignant diseases. Other authors also confirm this observation. Significant differences in the distribution of C-band regions have been reported for hematological malignancies, pre-leukemias, leukemias, myelomas and other hematological chromosomes. In this paper, heterochromatic regions of non-Hodgkin’s lymphoma (NHL) chromosomes 1, 9 and 16 were studied. 50 cases of newly diagnosed NHL, aged 8 to 77 years. The peripheral blood lymphocyte culture was used to investigate the abnormalities of chromosomes 1, 9 and 16. Use the Rapport classification to diagnose NHL. A total of 55 healthy individuals were randomly selected, ranging in age from 1 day to 45 years old, making up a control group. Use BSG technology