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有机磷农药中毒的治疗,传统的方法是反复应用较大剂量的阿托品及适当使用胆碱脂酶复活剂,但存在着易致阿托品中毒,注射次数频繁等问题。笔者按中国人民解放军军事医学科学院毒物药物研究所刘传馈的建议,使用以苯克磷为主的新疗法治疗有机磷农药中毒43例,取得较为满意的疗效,现报告如下。 一般资料 本组43例中男18例,女25例,年龄平均30.2岁;中毒途径除2例皮肤吸收,余均为口眼中毒;有机磷种类有甲胺磷、乐果、氧化乐果,敌敌畏,新胺硫磷等,药名不详者5例;按丁训杰方法分度,本文轻度中毒20例,中度12例,重度11例;胆碱脂酶(CHE)活性在40～10％之间。
Organophosphorus pesticide poisoning treatment, the traditional method is repeated use of larger doses of atropine and the proper use of cholinesterase resuscitator, but there is prone to atropine poisoning, frequent injections and other issues. The author according to the Chinese Academy of Military Medical Sciences Institute of Toxicology and Drugs Liu Chuan feedback recommendations, the use of new drugs based on pilocarpine treatment of 43 cases of organophosphate pesticide poisoning, and achieved more satisfactory results, are as follows. General information The group of 43 patients, 18 males and 25 females, average age of 30.2 years; poisoning pathway in addition to 2 cases of skin absorption, the rest are oral toxicity; organic phosphorus species are methamidophos, dimethoate, omethoate, Dichlorvos and new methamidophos, the unknown drug name in 5 cases; according to Dingxun Jie method of indexing, this article mild poisoning in 20 cases, moderate in 12 cases, severe in 11 cases; cholinesterase (CHE) activity in 40 to 10% between.