Brain cell apoptosis and enhancement of nervous excitability in pregnant rats with high plasma level

• 作 者: Jun Wang Jing Ge Liu Yang Haiy
• 机 构: DepartmentofGynaecologyandObstetrics,DepartmentofGynaecologyandObstetrics,ShenyangWomenandChildrenHe
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2012年28期
• 关键词: 高同型半胱氨酸血症 细胞凋亡 大鼠模型 兴奋性 怀孕 血浆 神经 额叶皮层 hyperhomocysteinemia homocysteine preeclam
• 基金项目: Funding： This project was funded by the General Project of Medical Technology of Military during the ＂12th Five-Year Plan＂ Period, No. CWS11J00.

Hyperhomocysteinemia is an important risk factor for preeclampsia-eclampsia. This study established a pregnant rat model of hyperhomocysteinemia, in which blood plasma homocysteine concentrations were twice or three times greater than that of normal pregn